Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 17/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 16/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17714357 | 0.96 | TDO2 (0.40) | FEN1ALOX5APTDO2HTR2AHTR2C | |
| SCHEMBL19723920 | 0.94 | TDO2 (0.42) | FEN1ALOX5APTDO2 | |
| SCHEMBL28146445 | 0.92 | ALOX5AP (0.31) | FEN1ALOX5APTDO2 | |
| SCHEMBL30541520 | 0.83 | HTR2C (0.41) | HTR2C | |
| SCHEMBL31197270 | 0.81 | IKBKB (0.43) | HTR2AHTR2C | |
| SCHEMBL30541401 | 0.80 | HTR1D (0.43) | — | |
| SCHEMBL31542145 | 0.79 | IKBKB (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL30427187 | 0.77 | HTR2A (0.41) | HTR2A | |
| SCHEMBL28257315 | 0.76 | CEL (0.34) | FEN1ALOX5APHTR2AHTR2CHTR2B | |
| SCHEMBL31503386 | 0.76 | CEL (0.34) | FEN1ALOX5APHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470934-B | Kinases inhibitor | 爱仕达生物技术有限责任公司 | 2017-08-04 | — | — | CN | claimed |
| CN-103002897-B | Certain amino-pyridazines, compositions thereof, and methods of use thereof | 赛特凯恩蒂克公司 | 2017-06-09 | — | — | CN | claimed |
| CN-104470934-B | Kinases inhibitor | 爱仕达生物技术有限责任公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-106795152-A | Protein kinase inhibitors | 安斯达尔生物技术有限责任公司 | 2017-05-31 | — | — | CN | disclosed |