Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 9/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17714357 | 0.98 | TDO2 (0.40) | TDO2FEN1CYP11B2ALOX5APNOTUM | |
| SCHEMBL28145355 | 0.94 | FEN1 (0.37) | TDO2FEN1ALOX5AP | |
| SCHEMBL28146445 | 0.90 | ALOX5AP (0.31) | TDO2FEN1ALOX5AP | |
| SCHEMBL30541520 | 0.81 | HTR2C (0.41) | — | |
| SCHEMBL31197270 | 0.80 | IKBKB (0.43) | — | |
| SCHEMBL30541401 | 0.79 | HTR1D (0.43) | — | |
| SCHEMBL2355698 | 0.78 | CEL (0.37) | TDO2CYP11B2NOTUMNISCHCYP2C19 | |
| SCHEMBL31542145 | 0.77 | IKBKB (0.46) | — | |
| SCHEMBL9600106 | 0.77 | TDO2 (0.35) | TDO2CYP11B2BACE1NOTUMCYP2C19 | |
| SCHEMBL18192194 | 0.75 | NOS1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144300-B1 | METHODS OF PRODUCING 4-CYCLOALKYLOXYBENZENESULFONAMIDES | DAIICHI SANKYO CO LTD (JP) | 2017-12-20 | — | — | EP | disclosed |