Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28858647 | 0.98 | ACMSD (0.41) | ACMSDKDM4EGLAHTTKMT2A | |
| SCHEMBL27764635 | 0.92 | MAPT (0.41) | ACMSDKDM4EKMT2ATDP1L3MBTL1 | |
| SCHEMBL5517327 | 0.87 | ACMSD (0.43) | ACMSDKDM4EGLAHTTKMT2A | |
| SCHEMBL14989243 | 0.86 | ACMSD (0.47) | ACMSDKDM4EGLAHTTKMT2A | |
| SCHEMBL27544733 | 0.86 | HTR2C (0.40) | KMT2AMAPTNOTUM | |
| SCHEMBL812111 | 0.82 | ACMSD (0.53) | ACMSDKDM4EGLAHTTKMT2A | |
| SCHEMBL6384930 | 0.82 | ACMSD (0.44) | ACMSDKDM4EGLAHTTKMT2A | |
| SCHEMBL28090456 | 0.80 | NPC1 (0.34) | ACMSDKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL28844067 | 0.80 | TAS1R3 (0.44) | ACMSDKDM4EGLAHTTKMT2A | |
| SCHEMBL18304680 | 0.79 | CXCR5 (0.55) | ACMSDKDM4EGLAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104583197-B | New bicyclicpyridine derivatives | 霍夫曼-拉罗奇有限公司 | 2017-05-17 | — | — | CN | claimed |
| CN-107835812-A | Target mutant K RAS composition and method | 南特生物科学股份有限公司 | 2018-03-23 | — | — | CN | disclosed |
| CN-104583197-B | New bicyclicpyridine derivatives | 霍夫曼-拉罗奇有限公司 | 2017-05-17 | — | — | CN | disclosed |