Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.38 |
| ▸ | HAAO | P46952 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28858647 | 0.93 | ACMSD (0.41) | MAPTNOTUMHAAOALDH1A1KDM4E | |
| SCHEMBL28145476 | 0.92 | ACMSD (0.43) | MAPTNOTUMKDM4ETDP1L3MBTL1 | |
| SCHEMBL27544733 | 0.90 | HTR2C (0.40) | MAPTNOTUMKMT2A | |
| SCHEMBL7080684 | 0.80 | CYP1A2 (0.48) | MAPTNOTUMALDH1A1CYP1A2KDM4E | |
| SCHEMBL2502722 | 0.80 | MAPT (0.42) | MAPTNOTUMHAAOALDH1A1CYP1A2 | |
| SCHEMBL27811967 | 0.79 | HAAO (0.35) | NOTUMHAAOALDH1A1CYP1A2KDM4E | |
| SCHEMBL5517327 | 0.78 | ACMSD (0.43) | MAPTHAAOALDH1A1KDM4EHPGD | |
| SCHEMBL29056921 | 0.76 | ALDH1A1 (0.58) | MAPTNOTUMALDH1A1CYP1A2KDM4E | |
| SCHEMBL14989243 | 0.76 | ACMSD (0.47) | CYP1A2KDM4ETDP1L3MBTL1KMT2A | |
| SCHEMBL18486812 | 0.76 | ESR2 (0.42) | MAPTNOTUMALDH1A1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106467589-A | A kind of catalytic component for vinyl polymerization, its preparation method and application | 中国石油化工股份有限公司 | 2017-03-01 | — | — | CN | claimed |
| CN-101454289-B | Substituted tetrahydroisoquinoline compounds, their preparation and use in medicine | ESTEVE LABOR DR | 2012-07-04 | — | — | CN | claimed |
| CN-101454289-A | Substituted tetrahydroisoquinoline compounds, their preparation and use in medicine | ESTEVE LABOR DR (ES) | 2009-06-10 | — | — | CN | claimed |
| CN-107835812-A | Target mutant K RAS composition and method | 南特生物科学股份有限公司 | 2018-03-23 | — | — | CN | disclosed |
| CN-106661043-A | 2-oxa-5-azabicyclo[2.2.1]heptan-3-yl derivatives | 豪夫迈·罗氏有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-106467589-A | A kind of catalytic component for vinyl polymerization, its preparation method and application | 中国石油化工股份有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-103874697-A | Dibenzooxepin derivative | KYOWA HAKKO KIRIN CO LTD | 2014-06-18 | — | — | CN | disclosed |
| CN-103517898-A | Novel 3-hydroxyisothiazole 1-oxide derivatives | MOCHIDA PHARM CO LTD | 2014-01-15 | — | — | CN | disclosed |
| CN-101454289-B | Substituted tetrahydroisoquinoline compounds, their preparation and use in medicine | ESTEVE LABOR DR | 2012-07-04 | — | — | CN | disclosed |
| CN-101454289-A | Substituted tetrahydroisoquinoline compounds, their preparation and use in medicine | ESTEVE LABOR DR (ES) | 2009-06-10 | — | — | CN | disclosed |