Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.51 |
| ▸ | CCR8 | P51685 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45253 | 0.81 | TDP1 (0.61) | CYP2C19ALDH1A1TDP1 | |
| SCHEMBL17974306 | 0.79 | ACHE (0.46) | CYP1A2CYP2D6PPARGPPARATSHR | |
| SCHEMBL31618736 | 0.78 | FFAR1 (0.52) | CETPCCR8PTGESTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL17960767 | 0.78 | ACHE (0.45) | CYP1A2CYP2D6PPARGPPARATSHR | |
| SCHEMBL10418763 | 0.76 | CYP1A2 (0.73) | PTGESCYP1A2NPC1CYP3A4CYP2D6 | |
| SCHEMBL11193556 | 0.76 | CYP1A2 (0.52) | CYP1A2NPC1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29729966 | 0.75 | MMP1 (0.56) | CETPCCR8PTGESALDH1A1TDP1 | |
| SCHEMBL5407250 | 0.73 | KDM4E (0.58) | CETPPTGESTSHRHSD17B10ALDH1A1 | |
| SCHEMBL10106163 | 0.73 | FDFT1 (0.53) | CETPPTGESPPARGPPARAALDH1A1 | |
| SCHEMBL8694023 | 0.73 | FFAR1 (0.54) | CCR8PTGESPPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662004-B | Novel rebamipide prodrug, method for producing same, and usage thereof | 三进制药株式会社 | 2017-04-19 | — | — | CN | disclosed |