Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | IDO1 | P14902 | 9/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113451 | 0.84 | L3MBTL1 (0.53) | TDP1L3MBTL1IDO1NOS3NOS1 | |
| SCHEMBL28184258 | 0.83 | TDP1 (0.61) | TDP1L3MBTL1IDO1NOS3NOS1 | |
| SCHEMBL6963636 | 0.83 | TDP1 (0.59) | TDP1L3MBTL1IDO1NOS3NOS1 | |
| SCHEMBL29096144 | 0.82 | HDAC3 (0.51) | TDP1L3MBTL1IDO1NOS3NOS1 | |
| SCHEMBL24305963 | 0.82 | NOS1 (0.50) | TDP1IDO1NOS1PAMHDAC3 | |
| SCHEMBL7007017 | 0.81 | TDP1 (0.58) | TDP1L3MBTL1IDO1NOS3NOS1 | |
| SCHEMBL3048336 | 0.81 | TDP1 (0.79) | TDP1L3MBTL1IDO1NOS3NOS1 | |
| SCHEMBL28145754 | 0.81 | CETP (0.51) | TDP1CYP2C19ALDH1A1 | |
| SCHEMBL20389068 | 0.80 | IDO1 (0.53) | TDP1L3MBTL1IDO1CYP2C19GAA | |
| SCHEMBL10408777 | 0.80 | ALDH1A1 (0.48) | TDP1L3MBTL1CYP2C19ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978317-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | Syngenta Participations AG (CH) | 2016-02-03 | — | — | EP | claimed |
| WO-2014154486-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | WO | claimed |
| WO-2020159448-A1 | MOLECULAR RENAL PROBES FOR DETECTING ACUTE KIDNEY INJURY | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2020-08-06 | — | — | WO | disclosed |
| US-20160050930-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA LIMITED (UK) | 2016-02-25 | — | — | US | disclosed |
| US-20160050929-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA LIMITED (GB) | 2016-02-25 | — | — | US | disclosed |
| EP-2978317-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | Syngenta Participations AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978316-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | Syngenta Participations AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| CN-103328561-B | Electrically conductive rubber elastomer, charging member, and electrophotographic apparatus | CANON KK | 2014-12-10 | — | — | CN | disclosed |
| WO-2014154488-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154486-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | WO | disclosed |
| CN-103328561-A | Electrically conductive rubber elastomer, charging member, and electrophotographic apparatus | CANON KK | 2013-09-25 | — | — | CN | disclosed |
| EP-2556051-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS | Sumitomo Chemical Company, Limited (JP) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011126129-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-10-13 | — | — | WO | disclosed |
| CN-1173937-C | (3S,4S) and (3R,4R)-beta-methyl-gamma-hydroxy-alkyl nitrile and its preparation and use | 中国科学院上海有机化学研究所 | 2004-11-03 | — | — | CN | disclosed |
| CN-1146534-C | (4S,5S)-and (4R,5R)-gamma-methyl-delta-hydroxyl-alkanoic acid and its alkyl ester, preparation method and application | 中国科学院上海有机化学研究所 | 2004-04-21 | — | — | CN | disclosed |
| CN-1321632-A | (4S,5S)-and (4R,5R)-gamma-methyl-delta-hydroxyl-alkanoic acid and its alkyl ester, preparation method and application | SHANGHAI INST ORGANIC CHEM (CN) | 2001-11-14 | — | — | CN | disclosed |
| CN-1308054-A | (3S,4S) and (3R,4R)-beta-methyl-gamma-hydroxy-alkyl nitrile and its preparation and use | SHANGHAI INST ORGANIC CHEM (CN) | 2001-08-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160050929-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | DDT, CRY1, NISCH | TDP1 3177/4885L3MBTL1 347/4885IDO1 2448/4885 |
| US-20160050930-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | DDT, CRY1, NISCH | TDP1 3228/4885L3MBTL1 330/4885IDO1 2005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.