Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL27965567 | 0.95 | EPHX1 (0.32) | EPHX1TBXA2RALOX5 | |
| Sulfuric Acid SCHEMBL27965597 | 0.90 | INPP5A (0.35) | — | |
| SCHEMBL8976389 | 0.82 | EPHX1 (0.35) | EPHX1TBXA2RDAO | |
| Ammonia Solution, Strong SCHEMBL27956565 | 0.79 | EPHX1 (0.30) | EPHX1 | |
| SCHEMBL7440315 | 0.79 | EPHX1 (0.39) | EPHX1TBXA2RMETAP2DAO | |
| SCHEMBL27475440 | 0.79 | EPHX1 (0.39) | EPHX1TBXA2RMETAP2DAO | |
| SCHEMBL27985770 | 0.76 | EPHX1 (0.31) | EPHX1 | |
| Ammonia Solution, Strong SCHEMBL27956555 | 0.73 | — | — | |
| SCHEMBL9802627 | 0.70 | EPHX1 (0.38) | EPHX1TBXA2RMETAP2ALOX5DAO | |
| Sulfuric Acid SCHEMBL28012362 | 0.70 | ALOX5 (0.32) | EPHX1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958496-B | Process for preparing N-substituted 1H-pyrazole-5-formate compounds and derivatives thereof | 巴斯夫欧洲公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-103874694-A | Process for preparing N-substituted 1H-pyrazole-5-carbonyl chloride compounds | BASF SE | 2014-06-18 | — | — | CN | disclosed |