Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | C1R | P00736 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | C1S | P09871 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28147489 | 0.90 | ADORA2A (0.56) | MEN1KMT2AATMADORA2ANUDT1 | |
| SCHEMBL28147454 | 0.84 | ALDH1A1 (0.48) | MEN1KMT2AATMADORA2ANUDT1 | |
| SCHEMBL17412545 | 0.84 | MEN1 (0.64) | MEN1KMT2AATMADORA2ANUDT1 | |
| SCHEMBL13911018 | 0.84 | MEN1 (0.64) | MEN1KMT2AATMADORA2ANUDT1 | |
| SCHEMBL28146353 | 0.83 | KDM4E (0.49) | MEN1KMT2AATMADORA2ANUDT1 | |
| SCHEMBL9920500 | 0.82 | MEN1 (0.70) | MEN1KMT2AATMADORA2ANUDT1 | |
| SCHEMBL23009837 | 0.81 | ADORA2A (0.44) | MEN1KMT2AADORA2AMAPTGAA | |
| SCHEMBL31065529 | 0.80 | CYP1A2 (0.59) | MEN1KMT2AATMADORA2ANUDT1 | |
| SCHEMBL18171541 | 0.80 | L3MBTL1 (0.60) | MEN1KMT2AATMADORA2ANUDT1 | |
| SCHEMBL18698038 | 0.80 | CYP1A2 (0.60) | MEN1KMT2AATMADORA2ANUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632086-A | 2-(2-iodoaryl)quinazoline compound and preparation method thereof | 江西省林业科学院 | 2017-05-10 | — | — | CN | claimed |
| CN-106632086-B | 2- (2- iodo aryl) quinazoline compounds and preparation method thereof | 江西省林业科学院 | 2019-08-09 | — | — | CN | disclosed |
| CN-106632086-A | 2-(2-iodoaryl)quinazoline compound and preparation method thereof | 江西省林业科学院 | 2017-05-10 | — | — | CN | disclosed |