Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28146348 | 0.90 | MEN1 (0.55) | ADORA2AMEN1KMT2AATMNUDT1 | |
| SCHEMBL28147319 | 0.83 | CYP1A2 (0.57) | ADORA2ASCN9AMEN1KMT2AATM | |
| SCHEMBL28147443 | 0.82 | MEN1 (0.71) | ADORA2ASCN9AMEN1KMT2AATM | |
| SCHEMBL28147464 | 0.82 | MEN1 (0.71) | ADORA2ASCN9AMEN1KMT2AATM | |
| SCHEMBL31300371 | 0.80 | MEN1 (0.69) | ADORA2ASCN9AMEN1KMT2AATM | |
| SCHEMBL21281993 | 0.79 | ADORA2A (0.55) | ADORA2ASCN9AMEN1KMT2AATM | |
| SCHEMBL28147454 | 0.75 | ALDH1A1 (0.48) | ADORA2AMEN1KMT2AATMNUDT1 | |
| SCHEMBL17412545 | 0.74 | MEN1 (0.64) | ADORA2AMEN1KMT2AATMNUDT1 | |
| SCHEMBL13911018 | 0.74 | MEN1 (0.64) | ADORA2AMEN1KMT2AATMNUDT1 | |
| SCHEMBL28470784 | 0.74 | ADORA2A (0.56) | ADORA2ASCN9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632086-A | 2-(2-iodoaryl)quinazoline compound and preparation method thereof | 江西省林业科学院 | 2017-05-10 | — | — | CN | claimed |
| CN-106632086-B | 2- (2- iodo aryl) quinazoline compounds and preparation method thereof | 江西省林业科学院 | 2019-08-09 | — | — | CN | disclosed |
| CN-106632086-A | 2-(2-iodoaryl)quinazoline compound and preparation method thereof | 江西省林业科学院 | 2017-05-10 | — | — | CN | disclosed |