Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4156358 | 0.88 | HTT (0.49) | LMNAKMT2AMAPTMEN1NPC1 | |
| SCHEMBL7826555 | 0.82 | FEN1 (0.52) | LMNAKMT2AMAPTMEN1NPC1 | |
| SCHEMBL17398547 | 0.82 | LMNA (0.47) | LMNAKMT2AMAPTMEN1NPC1 | |
| SCHEMBL7081256 | 0.76 | LMNA (0.47) | LMNAKMT2AMAPTMEN1NPC1 | |
| SCHEMBL1680462 | 0.76 | PNMT (0.58) | LMNAMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30579047 | 0.75 | LMNA (0.44) | LMNAKMT2AMAPTMEN1NPC1 | |
| SCHEMBL1680353 | 0.75 | LMNA (0.44) | LMNAKMT2AMAPTMEN1NPC1 | |
| SCHEMBL25394579 | 0.75 | LMNA (0.43) | LMNAKMT2AMAPTMEN1NPC1 | |
| SCHEMBL1681321 | 0.73 | LMNA (0.48) | LMNAKMT2AMAPTMEN1NPC1 | |
| SCHEMBL5726791 | 0.73 | NAAA (0.46) | LMNAKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999479-A | It can be used as the heteroaryl compound of SUMO activating enzyme inhibitors | 米伦纽姆医药公司 | 2017-08-01 | — | — | CN | disclosed |