SCHEMBL28147148

SCHEMBL28147148

CO[Si](C)(CCCN)OCc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.39
IDO1 P14902 1/20 0.37
AGXT P21549 1/20 0.36
SSTR1 P30872 1/20 0.36
SSTR2 P30874 1/20 0.36
SSTR4 P31391 1/20 0.36
SSTR3 P32745 1/20 0.36
SSTR5 P35346 1/20 0.36
TSHR P16473 1/20 0.35
HTR2A P28223 2/20 0.34
CYP2A6 P11509 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
LOXL2 Q9Y4K0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31511846 0.92 MAOA (0.42) MAOAIDO1AGXTSSTR1SSTR2
SCHEMBL31511847 0.92 MAOA (0.42) MAOAIDO1AGXTSSTR1SSTR2
SCHEMBL16212927 0.83 IDO1 (0.42) MAOAIDO1AGXTTSHRHTR2A
SCHEMBL37640 0.82 MAOA (0.40) MAOAIDO1AGXTTSHRHTR2A
SCHEMBL28826482 0.81 TSHR (0.39) IDO1AGXTTSHR
Hydrochloric Acid SCHEMBL30589986 0.81 AGXT (0.40) MAOAIDO1AGXTTSHRHTR2A
SCHEMBL11600226 0.78 MAOA (0.45) MAOAIDO1AGXTTSHRHTR2A
SCHEMBL2367825 0.77 MAOA (0.43) MAOAIDO1AGXTSSTR1SSTR2
SCHEMBL28122843 0.77 LTA4H (0.38) IDO1AGXTTSHR
SCHEMBL28660676 0.76 MAOA (0.42) MAOAIDO1AGXTSSTR1SSTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022050170-A1 COMPOUND MATERIAL, MOLDED BODY, AND CURED PRODUCT OF COMPOUND MATERIAL 昭和電工マテリアルズ株式会社 2022-03-10 WO disclosed
CN-105131272-B Novel polymer particle and application thereof 三井化学株式会社 2018-05-04 CN disclosed
CN-107299352-A Metal conditioner 信越化学工业株式会社 2017-10-27 CN disclosed
CN-103261351-B Pressure-sensitive adhesive composition for optical film, pressure-sensitive adhesive layer for optical film, pressure-sensitive adhesive optical film, and image display device 日东电工株式会社 2017-05-17 CN disclosed