SCHEMBL28826482

SCHEMBL28826482

CCC[Si](C)(OC)OCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
IDO1 P14902 1/20 0.36
TP53 P04637 1/20 0.35
AGXT P21549 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAOB P27338 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.34
MAPK1 P28482 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
MAPT P10636 1/20 0.34
CETP P11597 3/20 0.34
CYP3A4 P08684 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28147148 0.81 MAOA (0.39) TSHRIDO1AGXT
SCHEMBL27716226 0.80 TSHR (0.40) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL8561798 0.80 TSHR (0.40) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL8561019 0.80 TSHR (0.40) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL16212927 0.80 IDO1 (0.42) TSHRIDO1AGXTALDH1A1MAOB
SCHEMBL16537581 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL18297913 0.79 TSHR (0.46) TSHRIDO1TP53AGXTALDH1A1
Benzylamine SCHEMBL29255677 0.79 LOXL2 (0.50) TSHRTP53MAOBCYP3A4
SCHEMBL28122843 0.78 LTA4H (0.38) TSHRIDO1AGXTALDH1A1MAPK1
SCHEMBL16536089 0.78 TP53 (0.36) TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105349020-A Low viscosity moisture cured polymer compositions with tensile and creep properties for Industrial coatings,adhesives and sealant applications SHANGHAI APHYS DONNTAL ADHESIVE TECHNOLOGY CO LTD 2016-02-24 CN claimed