Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24922866 | 0.65 | SIRT2 (0.47) | RAB9ATSHRLMNANPC1SMN1; SMN2 | |
| SCHEMBL11558597 | 0.64 | RAB9A (0.47) | RAB9ATSHRLMNANFKB1NFKB2 | |
| SCHEMBL1500435 | 0.63 | LMNA (0.39) | RAB9ATSHRLMNAPKMKDM4E | |
| SCHEMBL27361867 | 0.63 | RAB9A (0.49) | RAB9ATSHRLMNANPC1SMN1; SMN2 | |
| SCHEMBL28987820 | 0.60 | — | — | |
| SCHEMBL5815964 | 0.60 | — | — | |
| SCHEMBL8656142 | 0.60 | — | — | |
| SCHEMBL4975148 | 0.58 | HCAR2 (0.47) | RAB9ATSHRLMNANFKB1NFKB2 | |
| SCHEMBL20075881 | 0.58 | PREP (0.44) | TSHRLMNATP53PKMKDM4E | |
| SCHEMBL6275593 | 0.57 | TNFSF11 (0.67) | RAB9ATSHRLMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632124-A | Synthesis method of 5,5'-di(acetic ether)-3,3'-bi-1,2,4-oxadiazole | 西安近代化学研究所 | 2017-05-10 | — | — | CN | disclosed |
| CN-106632124-A | Synthesis method of 5,5'-di(acetic ether)-3,3'-bi-1,2,4-oxadiazole | 西安近代化学研究所 | 2017-05-10 | — | — | CN | disclosed |