Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875579 | 0.84 | TMPRSS15 (0.49) | RAB9ANPC1TMPRSS15L3MBTL1MAPT | |
| SCHEMBL6632393 | 0.82 | TMPRSS15 (0.55) | RAB9ANPC1TMPRSS15L3MBTL1MAPT | |
| SCHEMBL8305554 | 0.82 | TMPRSS15 (0.48) | RAB9ANPC1TMPRSS15L3MBTL1MAPT | |
| SCHEMBL9844093 | 0.81 | TMPRSS15 (0.47) | RAB9ANPC1TMPRSS15L3MBTL1MAPT | |
| SCHEMBL19520914 | 0.79 | TMPRSS15 (0.49) | RAB9ANPC1TMPRSS15L3MBTL1MAPT | |
| SCHEMBL27952188 | 0.78 | TMPRSS15 (0.45) | RAB9ANPC1TMPRSS15L3MBTL1MAPT | |
| SCHEMBL23723952 | 0.77 | TMPRSS15 (0.47) | RAB9ANPC1TMPRSS15L3MBTL1MAPT | |
| SCHEMBL836787 | 0.76 | L3MBTL1 (0.56) | RAB9ANPC1TMPRSS15L3MBTL1MAPT | |
| SCHEMBL22978691 | 0.73 | TSHR (0.49) | RAB9ANPC1TMPRSS15L3MBTL1MAPT | |
| SCHEMBL27810220 | 0.72 | ALDH1A1 (0.56) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051304-B | Imidazo [4,5-c ] quinoline derivatives as LRRK2 inhibitors | 辉瑞大药厂 | 2022-12-27 | — | — | CN | disclosed |
| CN-113330000-A | 3-carbonylamino-5-cyclopentyl-1 FI-pyrrole compound having inhibitory activity against CDK2 | 辉瑞公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-101405294-B | Compounds for Enzyme Inhibition | ONYX THERAPEUTICS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-101087794-B | Pharmaceutical compounds | HOFFMANN LA ROCHE | 2011-05-18 | — | — | CN | disclosed |
| CN-101868457-A | (3-hydroxy-4-amino-but-2-yl) -3- (2-thiazol-2-yl-pyrrolidine-1-carbonyl) benzamide derivatives and related compounds as beta-secretase inhibitors for use in therapy | COMENTIS INC | 2010-10-20 | — | — | CN | disclosed |
| CN-100543017-C | Keto-oxadiazole derivatives as cathepsin inhibitors | AVENTIS PHARMA INC (US) | 2009-09-23 | — | — | CN | disclosed |
| CN-100528846-C | Amine compounds and use thereof | KUREHA CHEMICAL IND CO LTD (JP) | 2009-08-19 | — | — | CN | disclosed |
| CN-101405294-A | Compounds for enzyme inhibition | PROTEOLIX INC (US) | 2009-04-08 | — | — | CN | disclosed |
| CN-1898219-A | Novel keto-oxadiazole derivatives as cathepsin inhibitors | AVENTIS PHARMA INC (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1646495-A | Amine compounds and use thereof | KUREHA CHEMICAL IND CO LTD (JP) | 2005-07-27 | — | — | CN | disclosed |
| CN-1068316-C | Process for synthesizing 5-methyl-isoxazole-3-carboxamide | KUNSHAN GENERAL PHARMACEUTICAL (CN) | 2001-07-11 | — | — | CN | disclosed |
| CN-1156723-A | Process for synthesizing 5-methyl-isoxazole-3-carboxamide | KUNSHAN GENERAL PHARMACEUTICAL (CN) | 1997-08-13 | — | — | CN | disclosed |