Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dimethylaminoethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.46 |
| ▸ | CA2 | P00918 | 9/20 | 0.46 |
| ▸ | CA9 | Q16790 | 8/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28179152 | 0.90 | DNM1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28178263 | 0.90 | DNM1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28179142 | 0.90 | DNM1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1637921 | 0.90 | DNM1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL6902484 | 0.90 | CA1 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28178269 | 0.90 | DNM1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL6902616 | 0.90 | DNM1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28179162 | 0.90 | DNM1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL6900022 | 0.90 | DNM1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28178261 | 0.90 | DNM1 (0.54) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107096542-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-29 | — | — | CN | claimed |
| CN-107051496-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-18 | — | — | CN | claimed |
| CN-107051487-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-18 | — | — | CN | claimed |
| CN-107020110-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-08 | — | — | CN | claimed |
| CN-107020123-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-08 | — | — | CN | claimed |
| CN-107008364-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-04 | — | — | CN | claimed |
| CN-107008363-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-04 | — | — | CN | claimed |
| CN-107008377-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-04 | — | — | CN | claimed |
| CN-107008370-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-04 | — | — | CN | claimed |
| CN-107159235-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-09-15 | — | — | CN | disclosed |
| CN-107159237-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-09-15 | — | — | CN | disclosed |
| CN-107096542-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-29 | — | — | CN | disclosed |
| CN-107051524-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-18 | — | — | CN | disclosed |
| CN-107051479-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-18 | — | — | CN | disclosed |
| CN-107008376-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-04 | — | — | CN | disclosed |
| CN-107008364-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-04 | — | — | CN | disclosed |
| CN-107008360-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-04 | — | — | CN | disclosed |
| CN-107008379-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-04 | — | — | CN | disclosed |
| CN-106984341-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-07-28 | — | — | CN | disclosed |
| CN-106984329-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-07-28 | — | — | CN | disclosed |