Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CHRND | Q07001 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30959783 | 1.00 | CHRNA1 (0.40) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL3565013 | 0.82 | ALDH1A1 (0.40) | HSD11B1CYP26A1RXRARXRBCYP26B1 | |
| SCHEMBL1256099 | 0.82 | CHEK2 (0.39) | CYP26A1RXRARXRBCYP26B1SMN1; SMN2 | |
| SCHEMBL27825774 | 0.80 | CHEK2 (0.38) | CYP26A1RXRARXRBCYP26B1SMN1; SMN2 | |
| SCHEMBL855229 | 0.76 | CHRNA1 (0.48) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL2287075 | 0.75 | CYP26A1 (0.33) | CYP26A1RXRARXRBCYP26B1CHEK2 | |
| SCHEMBL6437554 | 0.73 | CYP2A6 (0.40) | CYP26A1RXRARXRBCYP26B1ALDH1A1 | |
| SCHEMBL9618088 | 0.73 | MEN1 (0.46) | RXRAGAAMAPK1 | |
| SCHEMBL14778257 | 0.73 | GAA (0.46) | RXRAGAAMAPK1 | |
| SCHEMBL1542779 | 0.73 | PKM (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164846-A | Synthesis method of dexketoprofen, intermediate and application thereof | 南京卡文迪许生物工程技术有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-106748723-A | A kind of preparation method of Ketoprofen | 江苏工程职业技术学院 | 2017-05-31 | — | — | CN | claimed |
| CN-118164846-A | Synthesis method of dexketoprofen, intermediate and application thereof | 南京卡文迪许生物工程技术有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-118164846-A | Synthesis method of dexketoprofen, intermediate and application thereof | 南京卡文迪许生物工程技术有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-106748723-A | A kind of preparation method of Ketoprofen | 江苏工程职业技术学院 | 2017-05-31 | — | — | CN | disclosed |