Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3565013 | 0.91 | ALDH1A1 (0.40) | CYP26A1CYP26B1RXRARXRBCNR1 | |
| SCHEMBL3562339 | 0.89 | CNR1 (0.39) | CYP2A6CNR1PKMALDH1A1MAPK1 | |
| SCHEMBL21679404 | 0.82 | MAOA (0.38) | CYP26A1CYP26B1RXRARXRBALDH1A1 | |
| SCHEMBL587682 | 0.76 | TAAR1 (0.42) | CYP2A6TAAR1ALDH1A1CYP3A4KDM4E | |
| SCHEMBL15908233 | 0.75 | MAOB (0.40) | CYP26A1CYP26B1RXRARXRBCYP3A4 | |
| SCHEMBL1542779 | 0.75 | PKM (0.32) | PKM | |
| SCHEMBL15874277 | 0.75 | CHEK2 (0.43) | CYP2A6CYP26A1CYP26B1RXRARXRB | |
| SCHEMBL17378166 | 0.75 | ALDH1A1 (0.43) | CYP26A1CYP26B1RXRARXRBALDH1A1 | |
| SCHEMBL15874310 | 0.75 | KMT2A (0.43) | CYP26A1CYP26B1RXRARXRBCNR1 | |
| SCHEMBL235335 | 0.75 | ESR2 (0.44) | CYP26A1CYP26B1RXRARXRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943523-A2 | SILYLATED POLYARYLETHERKETONE AND METHOD FOR MANUFACTURING SAME | Perpetuum-Ebner GmbH & Co. Kg (DE) | 2015-11-18 | — | — | EP | disclosed |
| WO-2014108420-A2 | SILYLATED POLYARYLETHERKETONE AND METHOD FOR MANUFACTURING SAME | PERPETUUM-EBNER GMBH & CO. KG (DE) | 2014-07-17 | — | — | WO | disclosed |
| EP-1506959-A2 | Derivatised molecules for mass spectrometry | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2005-02-16 | — | — | EP | disclosed |