Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016312 | 0.85 | MEN1 (0.63) | KMT2AMEN1PKMMAPTNPC1 | |
| SCHEMBL4034758 | 0.84 | NPC1 (0.62) | KMT2AMEN1PKMMAPTNPC1 | |
| SCHEMBL6941009 | 0.82 | MEN1 (0.57) | KMT2AMEN1PKMMAPTNPC1 | |
| SCHEMBL2222503 | 0.78 | MEN1 (0.56) | KMT2AMEN1PKMMAPTNPC1 | |
| SCHEMBL14099477 | 0.78 | MAPT (0.68) | KMT2AMEN1PKMMAPTNPC1 | |
| SCHEMBL2634675 | 0.77 | MAPT (0.53) | KMT2AMEN1PKMMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL11755337 | 0.76 | NPC1 (0.60) | KMT2AMEN1PKMMAPTNPC1 | |
| SCHEMBL16879704 | 0.75 | MAPT (0.56) | KMT2AMEN1PKMMAPTNPC1 | |
| SCHEMBL16879705 | 0.75 | MAPT (0.56) | KMT2AMEN1PKMMAPTNPC1 | |
| SCHEMBL1620133 | 0.75 | MAPT (0.57) | KMT2AMEN1PKMMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104163791-B | N-pyridine (hetero) aryl amide compound and preparation method and application thereof | 湖南化工研究院 | 2017-05-03 | — | — | CN | disclosed |