Biguanide

Biguanide

SCHEMBL28148706

N=C(N)NC(=N)N.O=CCCCC=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.50
TSHR P16473 2/20 0.36
MAPT P10636 1/20 0.31
TRPV1 Q8NER1 2/20 0.31
FAAH O00519 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutaral SCHEMBL28202030 0.84 HIF1A (0.62) HIF1ATSHRMAPTTRPV1FAAH
SCHEMBL261594 0.76
Glutaral SCHEMBL8758361 0.75 HIF1A (0.67) HIF1ATSHRMAPTTRPV1FAAH
SCHEMBL436282 0.75 ALOX15 (0.47) HIF1ATSHRMAPTTRPV1FAAH
SCHEMBL1774553 0.73 MEN1 (0.50) HIF1ATSHRTRPV1FAAH
SCHEMBL5497459 0.73 MEN1 (0.50) HIF1ATSHRTRPV1FAAH
SCHEMBL6673752 0.73 HIF1A (0.36) HIF1ATSHR
SCHEMBL7435959 0.73 MEN1 (0.50) HIF1ATSHRTRPV1FAAH
SCHEMBL7283602 0.73 MEN1 (0.50) HIF1ATSHRTRPV1FAAH
Glutaral SCHEMBL9577814 0.73 HIF1A (0.62) HIF1ATSHRMAPTTRPV1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106857685-A A kind of composition of disinfectant and preparation method thereof 新昌县派特普科技有限公司 2017-06-20 CN disclosed