SCHEMBL436282

SCHEMBL436282

N=C(N)NCCCCC=O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.47
MEN1 O00255 1/20 0.47
CYP1A2 P05177 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HIF1A Q16665 2/20 0.38
TSHR P16473 3/20 0.34
ALB P02768 1/20 0.34
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32
FAAH O00519 2/20 0.31
TRPV1 Q8NER1 1/20 0.31
SPHK1 Q9NYA1 3/20 0.31
MAPT P10636 1/20 0.30
SLC6A5 Q9Y345 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7435959 0.98 MEN1 (0.50) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL30374046 0.98 ALOX15 (0.46) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL7283602 0.98 MEN1 (0.50) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL5497459 0.98 MEN1 (0.50) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL1774553 0.98 MEN1 (0.50) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL261594 0.93
SCHEMBL17384745 0.84 ALOX15 (0.48) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL4318601 0.84
SCHEMBL28356938 0.83 ALOX15 (0.38) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL7380515 0.83 ALOX15 (0.47) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100305198-A1 CATIONIC LIPIDS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURG (GB) 2010-12-02 US claimed
EP-2212279-A1 CATIONIC LIPIDS The University Court Of The University of Edinburgh (GB) 2010-08-04 EP claimed
WO-2009050483-A1 CATIONIC LIPIDS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2009-04-23 WO claimed
EP-0334244-A2 Bradykinin Antagonist Peptides THE PROCTER & GAMBLE COMPANY (US) 1989-09-27 EP claimed
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS TRUSTEES OF TUFTS COLLEGE 2026-01-08 US disclosed
US-20250340591-A1 COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASE CONTAINING NOVEL COMPOUND ANYGEN CO LTD (KR) 2025-11-06 US disclosed
US-11779602-B2 Methods of use for CAR T cells ENDOCYTE, INC. (US) 2023-10-10 US disclosed
US-11779602-B2 Methods of use for CAR T cells ENDOCYTE, INC. (US) 2023-10-10 US disclosed
US-11759480-B2 Compositions and methods for CAR T cell therapy ENDOCYTE, INC. (US) 2023-09-19 US disclosed
US-11759480-B2 Compositions and methods for CAR T cell therapy ENDOCYTE, INC. (US) 2023-09-19 US disclosed
US-20220175875-A1 METHODS OF TREATING CANCER BY TARGETING TUMOR-ASSOCIATED MACROPHAGES ENDOCYTE INC (US) 2022-06-09 US disclosed
US-11311576-B2 Methods of use for CAR T cells SEATTLE CHILDREN'S HOSPITAL (US) 2022-04-26 US disclosed
EP-0464517-A2 Amino acid derivatives with renin inhibiting activity MERCK PATENT GmbH (DE) 1992-01-08 EP disclosed
EP-0456039-A2 Renin inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1991-11-13 EP disclosed
EP-0446485-A2 Peptide analogues with renininhibiting activity MERCK PATENT GmbH (DE) 1991-09-18 EP disclosed
EP-0446751-A1 Glycolic acid derivatives MERCK PATENT GmbH (DE) 1991-09-18 EP disclosed
EP-0418696-A2 Derivatives of aminoacids MERCK PATENT GmbH (DE) 1991-03-27 EP disclosed
EP-0339483-A2 Renin inhbiting amino-acid derivatives MERCK PATENT GmbH (DE) 1989-11-02 EP disclosed
EP-0337334-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1989-10-18 EP disclosed
EP-0334244-A2 Bradykinin Antagonist Peptides THE PROCTER & GAMBLE COMPANY (US) 1989-09-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11311576-B2 Methods of use for CAR T cells CD47, CD4, CD2 ALOX15 2145/4885MEN1 3960/4885CYP1A2 4676/4885
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS FIBP, FRS2, FGFR1 ALOX15 4479/4885MEN1 691/4885CYP1A2 4702/4885
US-11759480-B2 Compositions and methods for CAR T cell therapy CD47, PBK, GZMB ALOX15 2537/4885MEN1 2451/4885CYP1A2 4876/4885
US-11779602-B2 Methods of use for CAR T cells CD47, CD4, CD2 ALOX15 2145/4885MEN1 3960/4885CYP1A2 4676/4885
US-20220175875-A1 METHODS OF TREATING CANCER BY TARGETING TUMOR-ASSOCIATED MACROPHAGES FOLR1, FOLR2, FOLH1 ALOX15 821/4885MEN1 1102/4885CYP1A2 2973/4885
US-20100305198-A1 CATIONIC LIPIDS CETP, LIPA, ABHD16A ALOX15 892/4885MEN1 1595/4885CYP1A2 4828/4885
US-20250340591-A1 COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASE CONTAINING NOVEL COMPOUND GPR39, FABP2, GPR119 ALOX15 969/4885MEN1 4772/4885CYP1A2 3576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.