Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674188 | 0.87 | — | — | |
| SCHEMBL261594 | 0.78 | — | — | |
| SCHEMBL27780414 | 0.74 | HIF1A (0.39) | HIF1ATSHR | |
| Biguanide SCHEMBL28148706 | 0.73 | HIF1A (0.50) | HIF1ATSHR | |
| SCHEMBL436282 | 0.72 | ALOX15 (0.47) | HIF1ATSHR | |
| Glutaral SCHEMBL28202030 | 0.71 | HIF1A (0.62) | HIF1ATSHR | |
| SCHEMBL3166180 | 0.71 | — | — | |
| SCHEMBL9539681 | 0.71 | LMNA (0.40) | TSHR | |
| SCHEMBL5497459 | 0.71 | MEN1 (0.50) | HIF1ATSHR | |
| SCHEMBL7283602 | 0.71 | MEN1 (0.50) | HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627925-B1 | TRYPSIN INHIBITORS | DENDREON CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| US-5714580-A | PROTECTING ALDEHYDE OF AMINOALDEHYDE (I.E. ARGININAL) WITH 4-(DIARYLMETHYL)-SEMICARBAZIDE FOR SUBSEQUENT PEPTIDE ALDEHYDE SYNTHESIS | CORVAS INTERNATIONAL, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0627925-A4 | TRYPSIN INHIBITORS. | CORVAS INT INC (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5534498-A | TREATMENT OF PANCREATITIS | CORVAS INTERNATIONAL, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0627925-A1 | TRYPSIN INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993014779-A1 | TRYPSIN INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1993-08-05 | — | — | WO | disclosed |