SCHEMBL2814910

SCHEMBL2814910

O=C(Cl)N(Cc1ccccc1)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.68
ALDH1A1 P00352 3/20 0.68
HTT P42858 2/20 0.68
RAB9A P51151 2/20 0.68
PAX8 Q06710 2/20 0.68
GLA P06280 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
TRPM8 Q7Z2W7 1/20 0.56
GAA P10253 1/20 0.51
TSHR P16473 1/20 0.51
PDK1 Q15118 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
JAK2 O60674 1/20 0.50
TSPO P30536 1/20 0.49
CHRM2 P08172 1/20 0.48
CHRM1 P11229 1/20 0.48
CHRM3 P20309 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1927016 0.85 ALDH1A1 (0.69) NPC1ALDH1A1HTTRAB9APAX8
SCHEMBL3698220 0.82 NPC1 (0.49) NPC1ALDH1A1HTTRAB9APAX8
SCHEMBL5452605 0.81 NPC1 (1.00) NPC1ALDH1A1HTTRAB9APAX8
SCHEMBL27522330 0.80 ALDH1A1 (0.62) NPC1ALDH1A1HTTRAB9APAX8
SCHEMBL1385749 0.80 ALDH1A1 (0.62) NPC1ALDH1A1HTTRAB9APAX8
Carbamic Acid SCHEMBL6468271 0.80 NPC1 (0.62) NPC1ALDH1A1HTTRAB9APAX8
SCHEMBL5694553 0.80 TSPO (0.72) NPC1ALDH1A1HTTRAB9APAX8
SCHEMBL10921379 0.80 ALDH1A1 (0.62) NPC1ALDH1A1HTTRAB9APAX8
SCHEMBL1385745 0.80 NPC1 (0.62) NPC1ALDH1A1HTTRAB9APAX8
SCHEMBL9679324 0.79 ALDH1A1 (0.52) NPC1ALDH1A1HTTRAB9APAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11965098-B2 Pressing mold friendly binder for lignocellulosic composites HUNTSMAN INTERNATIONAL LLC 2024-04-23 US disclosed
EP-2734364-B1 BINDER COMPOSITION FOR USE IN CELLULOSIC COMPOSITES AND METHODS RELATED THERETO HUNTSMAN INT LLC (US) 2023-04-26 EP disclosed
US-20200277499-A1 PRESSING MOLD FRIENDLY BINDER FOR LIGNOCELLULOSIC COMPOSITES HUNTSMAN INTERNATIONAL LLC 2020-09-03 US disclosed
EP-3687677-A1 PRESSING MOLD FRIENDLY BINDER FOR LIGNOCELLULOSIC COMPOSITES Huntsman International LLC (US) 2020-08-05 EP disclosed
CN-111163860-A Compression-molding friendly adhesive for lignocellulosic composites 亨斯迈国际有限责任公司 2020-05-15 CN disclosed
WO-2019067201-A1 PRESSING MOLD FRIENDLY BINDER FOR LIGNOCELLULOSIC COMPOSITES HUNTSMAN INTERNATIONAL LLC (US) 2019-04-04 WO disclosed
US-9505711-B2 Method for purifying mixtures comprising 4,4′-methylenediphenyl diisocyanate BASF SE (DE) 2016-11-29 US disclosed
US-9505711-B2 Method for purifying mixtures comprising 4,4′-methylenediphenyl diisocyanate BASF SE (DE) 2016-11-29 US disclosed
EP-2640696-B1 PROCESS FOR PURIFYING MIXTURES COMPRISING 4,4'-METHYLENE DIPHENYL DIISOCYANATE BASF SE (DE) 2016-08-10 EP disclosed
EP-2640695-B1 PROCESS FOR PURIFYING MIXTURES COMPRISING 4,4'-METHYLENE DIPHENYL DIISOCYANATE BASF SE (DE) 2015-01-07 EP disclosed
US-20040266816-A1 Quinuclidine carbamate derivatives and their use as M3 antagonists ALMIRALL, S.A. (ES) 2004-12-30 US disclosed
US-20040242629-A1 Quinuclidine carbamate derivatives and their use as M3 antagonists LABORATORIOS ALMIRALL S.A. (ES) 2004-12-02 US disclosed
WO-2004000840-A2 QUINUCLIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME ALMIRALL PRODESFARMA AG (CH) 2003-12-31 WO disclosed
EP-1345937-A1 QUINUCLIDINE CARBAMATE DERIVATIVES AND THEIR USE AS M3 ANTAGONISTS Almirall Prodesfarma, S.A. (ES) 2003-09-24 EP disclosed
WO-2002051841-A1 QUINUCLIDINE CARBAMATE DERIVATIVES AND THEIR USE AS M3 ANTAGONISTS ALMIRALL PRODESFARMA AG (CH) 2002-07-04 WO disclosed
US-4136180-A HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS PFIZER INC. (US) 1979-01-23 US disclosed
US-4088766-A PRODUCTION OF PROSTAGLANDINS IN MAMMALS THE UPJOHN COMPANY (US) 1978-05-09 US disclosed
US-4062960-A Hypolipidemic alkenesulfonamides PFIZER INC. (US) 1977-12-13 US disclosed
US-4001256-A PROSTAGLANDIN PRODUCTION IN MAMMALS THE UPJOHN COMPANY (US) 1977-01-04 US disclosed
US-3983107-A ARTERIOSCLEROSIS PFIZER INC. (US) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242629-A1 Quinuclidine carbamate derivatives and their use as M3 antagonists CHRM3, CHRM2, CHRM1 NPC1 1428/4885ALDH1A1 1591/4885HTT 4041/4885
US-20040266816-A1 Quinuclidine carbamate derivatives and their use as M3 antagonists CHRM3, CHRM1, CHRM2 NPC1 1564/4885ALDH1A1 1413/4885HTT 3987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.