Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSPO | P30536 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927016 | 0.94 | ALDH1A1 (0.69) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL1385749 | 0.88 | ALDH1A1 (0.62) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL28986105 | 0.86 | NPC1 (0.61) | NPC1ALDH1A1GLAHTTRAB9A | |
| Hydrochloric Acid SCHEMBL27540694 | 0.86 | NPC1 (0.61) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL4443147 | 0.85 | NPC1 (0.54) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL22289326 | 0.84 | GAA (0.73) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL28926571 | 0.84 | NPC1 (0.54) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL1259310 | 0.82 | PDK1 (0.58) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL28807373 | 0.82 | GAA (0.70) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL7084586 | 0.81 | PRSS1 (0.56) | NPC1ALDH1A1GLAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | WYETH (US) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203176-A1 | Carbamates as HIV anti-viral agents | RNASEH1, CTSH, RNASE1 | NPC1 1339/4885ALDH1A1 2591/4885GLA 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.