8-Hydroxy Quinaldine

8-Hydroxy Quinaldine

SCHEMBL28149591

Cc1ccc2cccc(O)c2n1.[AlH2]Oc1ccccc1-c1ccccc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.59
LMNA P02545 3/20 0.44
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.40
KDM4E B2RXH2 4/20 0.39
BDKRB2 P30411 1/20 0.38
HTT P42858 1/20 0.38
PLAU P00749 1/20 0.38
NCF1 P14598 1/20 0.38
ECE2 P0DPD6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy Quinaldine SCHEMBL3483081 0.87 METAP2 (0.59) METAP2LMNACRHBPCRHR2TSHR
8-Hydroxy Quinaldine SCHEMBL6117507 0.87 METAP2 (0.59) METAP2LMNACRHBPCRHR2TSHR
2-Phenylphenol SCHEMBL28154200 0.85 METAP2 (0.72) METAP2LMNACRHBPCRHR2KMT2A
2-Phenylphenol SCHEMBL7203851 0.85 METAP2 (0.72) METAP2LMNACRHBPCRHR2KMT2A
2-Phenylphenol SCHEMBL2439345 0.84 METAP2 (0.70) METAP2LMNACRHBPCRHR2KMT2A
8-Hydroxy Quinaldine SCHEMBL4564944 0.84 METAP2 (0.70) METAP2LMNACRHBPCRHR2KMT2A
2-Phenylphenol SCHEMBL6759033 0.84 METAP2 (0.70) METAP2LMNACRHBPCRHR2KMT2A
8-Hydroxy Quinaldine SCHEMBL2436866 0.82 METAP2 (0.68) METAP2LMNACRHBPCRHR2KMT2A
8-Hydroxy Quinaldine SCHEMBL28962172 0.82 METAP2 (0.68) METAP2LMNACRHBPCRHR2KMT2A
8-Hydroxy Quinaldine SCHEMBL28331086 0.82 METAP2 (0.82) METAP2LMNATSHRSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106848083-B A kind of OLED display panel, preparation method and the electronic equipment comprising it 上海天马有机发光显示技术有限公司 2018-10-30 CN disclosed
CN-106848084-A A kind of OLED display panel, preparation method and the electronic equipment containing it 上海天马有机发光显示技术有限公司 2017-06-13 CN disclosed
CN-106848083-A A kind of OLED display panel, preparation method and the electronic equipment comprising it 上海天马有机发光显示技术有限公司 2017-06-13 CN disclosed