8-Hydroxy Quinaldine

8-Hydroxy Quinaldine

SCHEMBL4564944

Cc1ccc2cccc(O)c2n1.Cc1ccc2cccc(O)c2n1.Oc1c(-c2ccccc2)cccc1-c1ccccc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.70
KDM4E B2RXH2 3/20 0.44
KMT2A Q03164 3/20 0.44
PLAU P00749 1/20 0.44
NCF1 P14598 1/20 0.44
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
BCL2L1 Q07817 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX12 P18054 1/20 0.42
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 1/20 0.42
PARP1 P09874 1/20 0.42
CCR1 P32246 1/20 0.41
RAB9A P51151 1/20 0.41
CCR5 P51681 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy Quinaldine SCHEMBL2436866 0.98 METAP2 (0.68) METAP2KDM4EKMT2APLAUNCF1
2-Phenylphenol SCHEMBL28154200 0.92 METAP2 (0.72) METAP2KDM4EKMT2APLAUNCF1
2-Phenylphenol SCHEMBL7203851 0.92 METAP2 (0.72) METAP2KDM4EKMT2APLAUNCF1
2-Phenylphenol SCHEMBL2439345 0.91 METAP2 (0.70) METAP2KDM4EKMT2APLAUNCF1
2-Phenylphenol SCHEMBL6759033 0.91 METAP2 (0.70) METAP2KDM4EKMT2APLAUNCF1
8-Hydroxy Quinaldine SCHEMBL28962172 0.90 METAP2 (0.68) METAP2KDM4EKMT2APLAUNCF1
8-Hydroxy Quinaldine SCHEMBL28331086 0.89 METAP2 (0.82) METAP2KDM4EKMT2APLAUNCF1
8-Hydroxy Quinaldine SCHEMBL2438016 0.89 METAP2 (0.62) METAP2KDM4EKMT2APLAUNCF1
8-Hydroxy Quinaldine SCHEMBL28137990 0.87 METAP2 (0.79) METAP2KDM4EKMT2APLAUNCF1
8-Hydroxy Quinaldine SCHEMBL28232127 0.87 METAP2 (0.79) METAP2KDM4EKMT2APLAUNCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723263-B2 Organic electroluminescent element KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-08 US disclosed
US-11647666-B2 Organic electroluminescent element KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-05-09 US disclosed
US-20230096132-A1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-30 US disclosed
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-07 US disclosed
US-11407774-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-08-09 US disclosed
US-11342506-B2 Organic electroluminescent element KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-05-24 US disclosed
EP-3960744-A1 CYCLOALKANE-CONDENSED POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2022-03-02 EP disclosed
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-15 US disclosed
US-20210167288-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2021-06-03 US disclosed
US-20200266350-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-08-20 US disclosed
US-20190280209-A1 ORGANIC ELECTROLUMINESCENT ELEMENT JNC CORPORATION (JP) 2019-09-12 US disclosed
US-20190256538-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2019-08-22 US disclosed
US-20190207112-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2019-07-04 US disclosed
US-20190181350-A1 DEUTERIUM-SUBSTITUTED POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2019-06-13 US disclosed
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT JNC CORPORATION (JP) 2019-05-30 US disclosed
US-20190058124-A1 DELAYED FLUORESCENCE ORGANIC ELECTROLUMINESCENT ELEMENT Kwansei Gakuin Educational Fondation (JP) 2019-02-21 US disclosed
US-20180301629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-10-18 US disclosed
US-8324800-B2 Phosphorescent OLED device with mixed hosts GLOBAL OLED TECHNOLOGY LLC (US) 2012-12-04 US disclosed
US-20090309487-A1 PHOSPHORESCENT OLED DEVICE WITH MIXED HOSTS GLOBAL OLED TECHNOLOGY LLC 2009-12-17 US disclosed
EP-1736476-A1 NOVEL COMPOUND AND ORGANIC ELECTRONIC DEVICE USING SUCH COMPOUND Mitsui Chemicals, Inc. (JP) 2006-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus TYR, AOC2, AOC1 METAP2 2517/4885KDM4E 2025/4885KMT2A 1636/4885
US-20210167288-A1 POLYCYCLIC AROMATIC COMPOUND ARNT, TYR, AHR METAP2 2952/4885KDM4E 1577/4885KMT2A 1376/4885
US-20190181350-A1 DEUTERIUM-SUBSTITUTED POLYCYCLIC AROMATIC COMPOUND ARNT, ELOC, AHR METAP2 4331/4885KDM4E 1032/4885KMT2A 799/4885
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device AOC2, TYR, BMI1 METAP2 2679/4885KDM4E 1959/4885KMT2A 1499/4885
US-20230096132-A1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND LAGE3, ELOC, ELOB METAP2 3672/4885KDM4E 1841/4885KMT2A 1749/4885
US-20190207112-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NR4A3, AFF4, NR4A1 METAP2 4358/4885KDM4E 1262/4885KMT2A 2331/4885
US-11407774-B2 Polycyclic aromatic compound ETV6, EML4, EBPL METAP2 3897/4885KDM4E 717/4885KMT2A 792/4885
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, LGR4, OR51E2 METAP2 4028/4885KDM4E 396/4885KMT2A 2057/4885
US-11723263-B2 Organic electroluminescent element NR4A3, AFF4, NR4A1 METAP2 4358/4885KDM4E 1262/4885KMT2A 2331/4885
US-20190256538-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, EBPL METAP2 3897/4885KDM4E 717/4885KMT2A 792/4885
US-20180301629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, EPB41L2, EPB41 METAP2 4376/4885KDM4E 995/4885KMT2A 1823/4885
US-20190058124-A1 DELAYED FLUORESCENCE ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, REL, ELP1 METAP2 3953/4885KDM4E 1936/4885KMT2A 1905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.