8-Hydroxy Quinaldine

8-Hydroxy Quinaldine

SCHEMBL3483081

Cc1ccc2cccc(O)c2n1.Cc1ccc2cccc(O)c2n1.[Al]Oc1ccccc1-c1ccccc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.59
LMNA P02545 3/20 0.44
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.40
KDM4E B2RXH2 4/20 0.39
HTT P42858 1/20 0.38
PLAU P00749 1/20 0.38
NCF1 P14598 1/20 0.38
ECE2 P0DPD6 1/20 0.38
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy Quinaldine SCHEMBL6117507 1.00 METAP2 (0.59) METAP2LMNACRHBPCRHR2TSHR
8-Hydroxy Quinaldine SCHEMBL28149591 0.87 METAP2 (0.59) METAP2LMNACRHBPCRHR2TSHR
2-Phenylphenol SCHEMBL7203851 0.85 METAP2 (0.72) METAP2LMNACRHBPCRHR2KMT2A
2-Phenylphenol SCHEMBL28154200 0.85 METAP2 (0.72) METAP2LMNACRHBPCRHR2KMT2A
8-Hydroxy Quinaldine SCHEMBL4564944 0.84 METAP2 (0.70) METAP2LMNACRHBPCRHR2KMT2A
2-Phenylphenol SCHEMBL2439345 0.84 METAP2 (0.70) METAP2LMNACRHBPCRHR2KMT2A
2-Phenylphenol SCHEMBL6759033 0.84 METAP2 (0.70) METAP2LMNACRHBPCRHR2KMT2A
8-Hydroxy Quinaldine SCHEMBL28962172 0.82 METAP2 (0.68) METAP2LMNACRHBPCRHR2KMT2A
8-Hydroxy Quinaldine SCHEMBL2436866 0.82 METAP2 (0.68) METAP2LMNACRHBPCRHR2KMT2A
8-Hydroxy Quinaldine SCHEMBL28331086 0.82 METAP2 (0.82) METAP2LMNATSHRSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170263884-A1 ORGANIC LIGHT-EMITTING DIODE DISPLAY PANEL, FABRICATION METHOD, AND ELECTRONIC APPARATUS WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed
US-20100012926-A1 Organic electroluminescent device SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170263884-A1 ORGANIC LIGHT-EMITTING DIODE DISPLAY PANEL, FABRICATION METHOD, AND ELECTRONIC APPARATUS OCIAD1, OCIAD2, OPRD1 METAP2 3276/4885LMNA 3522/4885CRHBP 3097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.