Lucidumol A

Lucidumol A

SCHEMBL28150372

C[C@H](CC[C@H](O)C(C)(C)O)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@@H]1CC3=O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.59
CRYAB P02511 1/20 0.59
FNTA P49354 3/20 0.58
FNTB P49356 3/20 0.58
HMGCR P04035 1/20 0.51
NR1H4 Q96RI1 2/20 0.51
CES2 O00748 1/20 0.51
MEN1 O00255 1/20 0.49
PLA2G1B P04054 1/20 0.49
MAPT P10636 1/20 0.49
DNMT1 P26358 1/20 0.49
BLM P54132 1/20 0.49
KMT2A Q03164 1/20 0.49
ATG4B Q9Y4P1 1/20 0.49
PTGES O14684 1/20 0.44
PREP P48147 1/20 0.44
PIN1 Q13526 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lucidumol A SCHEMBL28150374 1.00 ACHE (0.59) ACHECRYABFNTAFNTBHMGCR
SCHEMBL29934928 0.92 ACHE (0.61) ACHECRYABFNTAFNTBHMGCR
SCHEMBL15934993 0.86 CRYAB (0.78) ACHECRYABFNTAFNTBNR1H4
Ganoderone A SCHEMBL29727694 0.81 ACHE (0.79) ACHECRYABFNTAFNTBHMGCR
Lucialdehyde B SCHEMBL30505329 0.81 FNTA (0.64) ACHECRYABFNTAFNTBHMGCR
Ganoderic Acid Dm SCHEMBL26959619 0.80 HMGCR (0.79) ACHECRYABFNTAFNTBHMGCR
SCHEMBL29934660 0.80 ACHE (0.67) ACHECRYABFNTAFNTBHMGCR
SCHEMBL29867370 0.78 HMGCR (0.59) ACHECRYABFNTAFNTBHMGCR
SCHEMBL29351229 0.76 ACHE (0.66) ACHECRYABFNTAFNTBHMGCR
Ganodermanondiol SCHEMBL30505330 0.74 ACHE (1.00) ACHECRYABFNTAFNTBHMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107056867-A Ganodenic acid compound, its Pharmaceutical composition and its application 峨眉山国芝堂生物科技有限公司 2017-08-18 CN disclosed