Ganoderic Acid Dm

Ganoderic Acid Dm

SCHEMBL26959619

C/C(=C/CC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@@H]1CC3=O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.79
MEN1 O00255 1/20 0.77
PLA2G1B P04054 1/20 0.77
MAPT P10636 1/20 0.77
DNMT1 P26358 1/20 0.77
BLM P54132 1/20 0.77
KMT2A Q03164 1/20 0.77
ATG4B Q9Y4P1 1/20 0.77
FNTA P49354 1/20 0.63
FNTB P49356 1/20 0.63
ACHE P22303 1/20 0.62
MAPK1 P28482 1/20 0.58
PTGES O14684 1/20 0.56
PREP P48147 1/20 0.56
PIN1 Q13526 1/20 0.56
CRYAB P02511 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ganoderone A SCHEMBL29727694 0.89 ACHE (0.79) HMGCRMEN1PLA2G1BMAPTDNMT1
Lucialdehyde B SCHEMBL30505329 0.89 FNTA (0.64) HMGCRMEN1PLA2G1BMAPTDNMT1
SCHEMBL23911676 0.88 HMGCR (1.00) HMGCRMEN1PLA2G1BMAPTDNMT1
SCHEMBL29867902 0.88 HMGCR (1.00) HMGCRMEN1PLA2G1BMAPTDNMT1
Anwuweizonic Acid SCHEMBL18687709 0.87 MAPT (1.00) HMGCRMEN1PLA2G1BMAPTDNMT1
Anwuweizonic Acid SCHEMBL20990961 0.87 MAPT (1.00) HMGCRMEN1PLA2G1BMAPTDNMT1
Anwuweizonic Acid SCHEMBL12474243 0.87 MAPT (1.00) HMGCRMEN1PLA2G1BMAPTDNMT1
Anwuweizonic Acid SCHEMBL6567253 0.87 MAPT (1.00) HMGCRMEN1PLA2G1BMAPTDNMT1
Anwuweizonic Acid SCHEMBL12474225 0.87 MAPT (1.00) HMGCRMEN1PLA2G1BMAPTDNMT1
Anwuweizonic Acid SCHEMBL12474223 0.87 MAPT (1.00) HMGCRMEN1PLA2G1BMAPTDNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118909817-A Genetically engineered bacterium for producing ganoderic acid DM, construction method and application thereof 北京化工大学 2024-11-08 CN claimed
CN-117838741-A Application of ganoderma lucidum alcohol extract in treating or relieving silicosis 四川大学 2024-04-09 CN claimed
CN-115737691-B Ganoderma lucidum strong effect component and preparation method thereof 浙江寿仙谷植物药研究院有限公司 2023-11-10 CN claimed
CN-116474006-A Application of ganoderma lucidum extract in preparing medicine for resisting SARS-CoV-2 virus 浙江农林大学 2023-07-25 CN claimed
CN-113917033-B Method for detecting neutral triterpene of ganoderma fungus 上海市农业科学院 2023-07-04 CN claimed
CN-115737691-A Ganoderma lucidum strong-effect component and preparation method thereof 浙江寿仙谷植物药研究院有限公司 2023-03-07 CN claimed
CN-112326853-B Method for simultaneously detecting 25 triterpene compounds in ganoderma lucidum fruiting body 上海市农业科学院 2022-10-11 CN claimed
CN-108866142-B Cytochrome P450, nicotinamide adenine dinucleotide-cytochrome P450 reductase and application thereof 中国科学院分子植物科学卓越创新中心 2022-08-16 CN claimed
CN-122005461-A Plant carbon point mouth drop powder and preparation method and application thereof 北京旭华时代科技有限公司 2026-05-12 CN disclosed
CN-121874277-A Lucid ganoderma fermentation preparation method of full-effect component and application thereof 杭州玥洋生物科技有限公司 2026-04-17 CN disclosed
CN-121243186-B Application of Asprosin small molecule inhibitor in preparation of medicine for preventing and/or treating diabetic nephropathy 南昌大学 2026-02-24 CN disclosed
CN-121243186-A Application of Asprosin small molecule inhibitor in preparation of medicine for preventing and/or treating diabetic nephropathy 南昌大学 2026-01-02 CN disclosed
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 US disclosed
CN-120919141-A Antitumor composition and preparation method thereof 上海市农业科学院 2025-11-11 CN disclosed
CN-115400049-A Hair care composition containing ganoderma sinense extract and application thereof 苏州猫尔科技有限公司 2022-11-29 CN disclosed
CN-112326853-B Method for simultaneously detecting 25 triterpene compounds in ganoderma lucidum fruiting body 上海市农业科学院 2022-10-11 CN disclosed
US-20220291237-A1 Gene Expression Inflammatory Age and Its Uses Edifice Health, Inc. (US) 2022-09-15 US disclosed
CN-108866142-B Cytochrome P450, nicotinamide adenine dinucleotide-cytochrome P450 reductase and application thereof 中国科学院分子植物科学卓越创新中心 2022-08-16 CN disclosed
CN-108866142-B Cytochrome P450, nicotinamide adenine dinucleotide-cytochrome P450 reductase and application thereof 中国科学院分子植物科学卓越创新中心 2022-08-16 CN disclosed
CN-114854662-A Method for increasing content of ganoderma lucidum low-polarity ganoderma lucidum triterpenes 南京农业大学 2022-08-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO HMGCR 562/4885MEN1 4581/4885PLA2G1B 138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.