SCHEMBL28150458

SCHEMBL28150458

CCO[Si](C)(CCCCCNCCN)OC(C)N

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.32
CA6 P23280 4/20 0.32
CA7 P43166 4/20 0.32
CA9 Q16790 4/20 0.32
CA14 Q9ULX7 4/20 0.32
CA5B Q9Y2D0 4/20 0.32
CA2 P00918 3/20 0.32
CA4 P22748 3/20 0.32
CA5A P35218 3/20 0.32
CA3 P07451 2/20 0.32
F13A1 P00488 2/20 0.31
CYP1A2 P05177 2/20 0.31
ALOX15 P16050 2/20 0.31
THPO P40225 2/20 0.31
MEN1 O00255 2/20 0.31
RECQL P46063 2/20 0.31
KMT2A Q03164 2/20 0.31
CYP2C19 P33261 1/20 0.31
CASP2 P42575 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27986342 0.85 DNM1 (0.32) MEN1KMT2AALDH1A1TSHR
SCHEMBL28343198 0.84 DNM1 (0.31) MEN1KMT2AALDH1A1TSHR
SCHEMBL9306230 0.82 CA12 (0.45) CA12CA6CA7CA9CA14
SCHEMBL28149494 0.81
SCHEMBL27776297 0.80 OPRM1 (0.39)
SCHEMBL37492 0.80 CA12 (0.42) CA12CA6CA7CA9CA14
SCHEMBL27831798 0.80 CA12 (0.33) CA12CA6CA7CA9CA14
SCHEMBL5433201 0.79 CA12 (0.45) CA12CA6CA7CA9CA14
SCHEMBL2616725 0.79 CA12 (0.45) CA12CA6CA7CA9CA14
SCHEMBL29915593 0.79 CA12 (0.32) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107022084-A A kind of new silicon-fluorine polymer thing and preparation method thereof and the surface conditioning agent comprising the polymer 苏州逸微光电科技有限公司 2017-08-08 CN claimed