Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396264 | 0.87 | L3MBTL1 (0.41) | PARP1MEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL17025091 | 0.82 | PARP1 (0.43) | PARP1ERCC5FEN1MEN1KMT2A | |
| SCHEMBL29961790 | 0.82 | PARP1 (0.43) | PARP1ERCC5FEN1MEN1KMT2A | |
| SCHEMBL28924563 | 0.80 | PBRM1 (0.52) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL29200432 | 0.79 | CES2 (0.55) | PARP1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL29200417 | 0.79 | PARP1 (0.52) | PARP1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL19398201 | 0.79 | PARP1 (0.52) | PARP1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13909938 | 0.77 | IDO1 (0.33) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL17454634 | 0.77 | KMO (0.55) | ERCC5FEN1MAPTGAA | |
| SCHEMBL30151360 | 0.77 | KMO (0.55) | ERCC5FEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-111662202-B | Synthetic method of alpha-ketoamide compound | 五邑大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-111662202-A | Synthetic method of alpha-ketoamide compound | 五邑大学 | 2020-09-15 | — | — | CN | disclosed |
| CN-106661043-A | 2-oxa-5-azabicyclo[2.2.1]heptan-3-yl derivatives | 豪夫迈·罗氏有限公司 | 2017-05-10 | — | — | CN | disclosed |