Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | LPL | P06858 | 2/20 | 0.54 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28313957 | 0.96 | SIGMAR1 (0.59) | SIGMAR1L3MBTL1LPLLIPGEPHX1 | |
| SCHEMBL6932623 | 0.87 | LPL (0.67) | LPLLIPG | |
| SCHEMBL27683349 | 0.87 | LPL (0.67) | LPLLIPG | |
| SCHEMBL11746219 | 0.87 | LPL (0.67) | LPLLIPG | |
| SCHEMBL10518886 | 0.87 | LPL (0.67) | LPLLIPG | |
| SCHEMBL5249436 | 0.87 | LPL (0.67) | LPLLIPG | |
| SCHEMBL4032533 | 0.87 | LPL (0.67) | LPLLIPG | |
| SCHEMBL29742685 | 0.87 | LPL (0.67) | LPLLIPG | |
| SCHEMBL8563196 | 0.87 | LPL (0.67) | LPLLIPG | |
| SCHEMBL4211261 | 0.87 | LPL (0.67) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715414-B | With 2 adrenaline excitant of β and the active new bicyclic derivatives of M3 muscarinic antagonist | 阿尔米雷尔有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-106715414-A | New bicyclic derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities | 阿尔米雷尔有限公司 | 2017-05-24 | — | — | CN | disclosed |