Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 11/20 | 0.69 |
| ▸ | PARP1 | P09874 | 5/20 | 0.69 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.69 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | GABRP | O00591 | 4/20 | 0.68 |
| ▸ | GABRD | O14764 | 4/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.68 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.68 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.68 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.68 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.68 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.68 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.68 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.68 |
| ▸ | GABRE | P78334 | 4/20 | 0.68 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311443 | 0.88 | FTO (0.73) | TNKSPARP1TNKS2MAOBPARP2 | |
| SCHEMBL312104 | 0.85 | TNKS (0.66) | TNKSPARP1TNKS2MAOBPARP2 | |
| Flavone SCHEMBL27686205 | 0.84 | TNKS (0.84) | TNKSPARP1TNKS2MAOBPARP2 | |
| Flavone SCHEMBL20581911 | 0.82 | TNKS (0.87) | TNKSPARP1TNKS2MAOBPARP2 | |
| SCHEMBL7593917 | 0.82 | TNKS (1.00) | TNKSPARP1TNKS2MAOBPARP2 | |
| Flavone SCHEMBL30542161 | 0.81 | TNKS (1.00) | TNKSPARP1TNKS2MAOBPARP2 | |
| Flavone SCHEMBL28248986 | 0.81 | TNKS (1.00) | TNKSPARP1TNKS2MAOBPARP2 | |
| Flavone SCHEMBL15676601 | 0.81 | TNKS (1.00) | TNKSPARP1TNKS2MAOBPARP2 | |
| Flavone SCHEMBL18879 | 0.81 | TNKS (1.00) | TNKSPARP1TNKS2MAOBPARP2 | |
| Flavone SCHEMBL31316377 | 0.81 | TNKS (1.00) | TNKSPARP1TNKS2MAOBPARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928207-A | Double target spot inhibitor of the α of tumour tubulin HIF 1 and preparation method thereof | 南华大学 | 2017-07-07 | — | — | CN | disclosed |