Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23247964 | 1.00 | RAB9A (0.47) | RAB9ASMN1; SMN2HCRTR1HCRTR2PDE10A | |
| SCHEMBL7329173 | 0.97 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL7329171 | 0.97 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL7330933 | 0.97 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL12509701 | 0.87 | CHEK2 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL12327656 | 0.85 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL12567373 | 0.85 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL17277682 | 0.85 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL16215441 | 0.85 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL15048040 | 0.84 | CHEK2 (0.42) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928126-B | Amide derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-106928126-A | A kind of amide derivatives and preparation method thereof and application pharmaceutically | 四川海思科制药有限公司 | 2017-07-07 | — | — | CN | disclosed |