Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 7/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.49 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329171 | 1.00 | HCRTR1 (0.49) | HCRTR1HCRTR2PTGES | |
| SCHEMBL7330933 | 1.00 | HCRTR1 (0.49) | HCRTR1HCRTR2PTGES | |
| SCHEMBL23247964 | 0.97 | RAB9A (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL28152181 | 0.97 | RAB9A (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL204876 | 0.87 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL12509692 | 0.87 | HCRTR1 (0.46) | HCRTR1HCRTR2PTGES | |
| SCHEMBL14985689 | 0.87 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL2707183 | 0.87 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL28590669 | 0.87 | USP30 (0.58) | HCRTR1HCRTR2 | |
| SCHEMBL19400821 | 0.87 | PRCP (0.52) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5977101-A | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |