SCHEMBL28152309

SCHEMBL28152309

C=CCOC(=O)C=C.O=S(=O)(O)C=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
GAA P10253 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP3A4 P08684 1/20 0.43
THRB P10828 1/20 0.42
CASP1 P29466 1/20 0.41
APP P05067 1/20 0.41
AKR1B10 O60218 1/20 0.40
AKR1B1 P15121 1/20 0.40
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 2/20 0.40
ALOX12 P18054 1/20 0.40
PPARG P37231 2/20 0.39
NFE2L2 Q16236 1/20 0.39
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28151211 0.87 PPARG (0.41) LMNAGAAMEN1KMT2AKDM4E
SCHEMBL15901443 0.85 TSHR (0.51) LMNAGAAMEN1KMT2ACYP3A4
SCHEMBL9300843 0.84 THRB (0.47) LMNAGAAMEN1KMT2AMAPT
Acrylic Acid Methyl Ester SCHEMBL7747737 0.81 HTT (0.46) LMNAGAAKMT2AALDH1A1PPARG
SCHEMBL28152774 0.81 CYP3A4 (0.46) LMNAGAAMEN1KMT2AKDM4E
Phosphoric Acid SCHEMBL21408821 0.81 TSHR (0.46) LMNAGAAMEN1KMT2AKDM4E
Styrene SCHEMBL167641 0.81 CYP3A4 (0.51) LMNAGAAMEN1KMT2AKDM4E
Acrylic Acid SCHEMBL17821214 0.80 HDAC3 (0.48) LMNAGAAMEN1KMT2AKDM4E
Acrylic Acid SCHEMBL1897633 0.80 HDAC3 (0.48) LMNAGAAMEN1KMT2AKDM4E
SCHEMBL87699 0.79 LMNA (0.44) LMNAGAAMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106793354-B A kind of luminous paint system 万峰 2018-06-22 CN disclosed
CN-106793354-A A kind of luminous paint system 万峰 2017-05-31 CN disclosed