Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2720751 | 0.81 | LMNA (0.44) | TDP1SCN5ATSHRHTR2AHTR2B | |
| SCHEMBL15649428 | 0.74 | TDP1 (0.36) | TDP1PARP10GAAHDAC1HDAC2 | |
| SCHEMBL7077662 | 0.70 | HPGD (0.54) | TDP1GAATSHRHTR2AHTR2C | |
| SCHEMBL10013408 | 0.70 | CXCL8 (0.42) | TSHRKMT2AIRAK4SMN1; SMN2ALDH1A1 | |
| SCHEMBL10013407 | 0.70 | CXCL8 (0.42) | TSHRKMT2AIRAK4SMN1; SMN2ALDH1A1 | |
| SCHEMBL400373 | 0.70 | CXCL8 (0.42) | TSHRKMT2AIRAK4SMN1; SMN2ALDH1A1 | |
| SCHEMBL2559228 | 0.70 | SRC (0.47) | TDP1PARP10GAAHDAC1HDAC2 | |
| SCHEMBL14447023 | 0.70 | TDP1 (0.51) | TDP1PARP10GAAHDAC1SMN1; SMN2 | |
| SCHEMBL14447011 | 0.70 | TDP1 (0.51) | TDP1PARP10GAAHDAC1SMN1; SMN2 | |
| SCHEMBL22418891 | 0.69 | IRAK4 (0.36) | TDP1SCN5APARP10IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928127-B | Substituted piperidine amide derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-106928127-A | Substituted piperidine class amide derivatives and preparation method thereof and application pharmaceutically | 四川海思科制药有限公司 | 2017-07-07 | — | — | CN | disclosed |