Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19322449 | 0.77 | MAPT (0.53) | MAPTLMNAALDH1A1POLBBLM | |
| SCHEMBL3946801 | 0.76 | MAPT (0.56) | MAPTLMNAALDH1A1POLBBLM | |
| SCHEMBL34121 | 0.76 | ALDH1A1 (0.68) | MAPTLMNAALDH1A1POLBBLM | |
| SCHEMBL3365278 | 0.76 | MAPT (0.56) | MAPTLMNAALDH1A1POLBBLM | |
| SCHEMBL5425653 | 0.76 | ALDH1A1 (0.68) | MAPTLMNAALDH1A1POLBBLM | |
| SCHEMBL9150171 | 0.76 | ALDH1A1 (0.68) | MAPTLMNAALDH1A1POLBBLM | |
| SCHEMBL2085581 | 0.74 | MAPT (0.69) | MAPTLMNAALDH1A1POLBBLM | |
| SCHEMBL951472 | 0.73 | ALKBH5 (0.73) | MAPTLMNAALDH1A1POLBBLM | |
| Methyl Alcohol SCHEMBL1028813 | 0.73 | MAPT (0.69) | MAPTLMNAALDH1A1POLBBLM | |
| SCHEMBL15440041 | 0.73 | MAPT (0.53) | MAPTLMNAALDH1A1POLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061313-B | Androgen receptor modulating compounds | 奥赖恩公司 | 2017-07-18 | — | — | CN | disclosed |