Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28207782 | 0.94 | LMNA (0.37) | LMNAL3MBTL1 | |
| SCHEMBL27599291 | 0.77 | ALDH1A1 (0.44) | GAAALDH1A1L3MBTL1 | |
| SCHEMBL12441738 | 0.73 | TSHR (0.42) | LMNAL3MBTL1 | |
| SCHEMBL75611 | 0.72 | HPGD (0.58) | HPGDGAALMNACA12CA1 | |
| SCHEMBL31518814 | 0.72 | HPGD (0.58) | HPGDGAALMNACA12CA1 | |
| SCHEMBL9162112 | 0.72 | HPGD (0.58) | HPGDGAALMNACA12CA1 | |
| SCHEMBL2727733 | 0.72 | HPGD (0.34) | HPGDGAALMNACHRM2CHRM4 | |
| Ammonia Solution, Strong SCHEMBL27259881 | 0.71 | HPGD (0.56) | HPGDGAALMNACA12CA1 | |
| SCHEMBL18639814 | 0.70 | HPGD (0.37) | HPGDGAACHRM2CHRM4CHRM5 | |
| SCHEMBL74963 | 0.70 | HPGD (0.37) | HPGDGAACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267957-A | Quinazoline compound | 安斯泰来制药株式会社 | 2019-09-20 | — | — | CN | disclosed |
| CN-106715419-A | Aminotriazine derivatives as TANK-binding kinase inhibitor compounds | 吉利德科学公司 | 2017-05-24 | — | — | CN | disclosed |