Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3734203 | 1.00 | TSHR (0.41) | TSHRACHELMNAARP2RX7 | |
| Isothiocyanate SCHEMBL6156341 | 0.86 | TSHR (0.41) | TSHRACHELMNAARALDH1A1 | |
| SCHEMBL14127455 | 0.84 | — | — | |
| SCHEMBL12792 | 0.84 | — | — | |
| SCHEMBL29432874 | 0.84 | — | — | |
| Formaldehyde SCHEMBL28159516 | 0.82 | TSHR (0.47) | TSHRACHELMNAP2RX7ALDH1A1 | |
| O-Xylene SCHEMBL163751 | 0.82 | TSHR (0.62) | TSHRACHELMNAALDH1A1CA1 | |
| 1,2-Dichlorobenzene SCHEMBL521767 | 0.82 | TSHR (0.62) | TSHRACHELMNAALDH1A1PLA2G7 | |
| Hydrochloric Acid SCHEMBL9527099 | 0.82 | — | — | |
| O-Xylene SCHEMBL31425598 | 0.82 | TSHR (0.62) | TSHRACHELMNAALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028446-A1 | ISOCYANATE COMPOSITION, MODIFIED COMPOSITION AND POLYURETHANE ELASTOMER | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2026-01-29 | — | — | US | disclosed |
| EP-4545582-A1 | ISOCYANATE COMPOSITION, MODIFIED COMPOSITION AND POLYURETHANE ELASTOMER | Wanhua Chemical Group Co., Ltd. (CN) | 2025-04-30 | — | — | EP | disclosed |
| CN-115746251-A | Isocyanate composition, modified composition and polyurethane elastomer | 万华化学集团股份有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115160096-A | Method for preparing aryl amide compound under conditions of no catalyst and no coupling agent | 湖北沙洋荆氟化工科技有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-110054577-B | Compound containing urea and thiourea structure, synthetic method and application thereof | 中国医学科学院放射医学研究所 | 2021-09-10 | — | — | CN | disclosed |
| CN-112111044-B | Polyisocyanate composition and preparation method and application thereof | 万华化学集团股份有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-112111044-A | Polyisocyanate composition and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-107176925-B | Synthesis method of polysubstituted imidazoline-2, 4-diketone compound | 湖北科技学院 | 2020-04-28 | — | — | CN | disclosed |
| US-9035087-B2 | Process for producing polyisocyanate | MITSUI CHEMICALS, INC. (JP) | 2015-05-19 | — | — | US | disclosed |
| EP-2210873-B1 | PROCESS FOR PRODUCING POLYISOCYANATE | MITSUI CHEMICALS INC (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-20100249450-A1 | PROCESS FOR PRODUCING POLYISOCYANATE | MITSUI CHEMICALS INC. | 2010-09-30 | — | — | US | disclosed |
| EP-2210873-A1 | PROCESS FOR PRODUCING POLYISOCYANATE | Mitsui Chemicals, Inc. (JP) | 2010-07-28 | — | — | EP | disclosed |
| US-6337338-B1 | INSULIN LIKE GROWTH FACTOR RECEPTOR IN MAMMALS | TELIK, INC. | 2002-01-08 | — | — | US | disclosed |
| WO-2000035455-A1 | HETEROARYL-ARYL UREAS AS IGF-1 RECEPTOR ANTAGONISTS | TELIK, INC. (US) | 2000-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028446-A1 | ISOCYANATE COMPOSITION, MODIFIED COMPOSITION AND POLYURETHANE ELASTOMER | ERCC2, IK, INCENP | TSHR 4583/4885ACHE 1099/4885LMNA 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.