Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679704 | 0.86 | MAPT (0.49) | MAPTTDP1PKMLMNACES2 | |
| SCHEMBL2226269 | 0.80 | MAPT (0.43) | MAPTTDP1PKMLMNACES2 | |
| SCHEMBL29384 | 0.79 | USP2 (0.52) | MAPTLMNACES2CES1ALDH1A1 | |
| Bicarbonate SCHEMBL1969232 | 0.78 | USP2 (0.51) | MAPTLMNACES2CES1ALDH1A1 | |
| Methoxymethane SCHEMBL28122245 | 0.78 | USP2 (0.51) | MAPTLMNACES2CES1ALDH1A1 | |
| Bicarbonate SCHEMBL31648960 | 0.78 | USP2 (0.51) | MAPTLMNACES2CES1ALDH1A1 | |
| SCHEMBL12587771 | 0.78 | MAPT (0.57) | MAPTTDP1LMNAALDH1A1L3MBTL1 | |
| Acetic Acid SCHEMBL8064561 | 0.77 | USP2 (0.50) | MAPTLMNACES2CES1ALDH1A1 | |
| Benzene SCHEMBL28180511 | 0.77 | USP2 (0.50) | MAPTLMNACES2CES1ALDH1A1 | |
| SCHEMBL17785925 | 0.76 | LMNA (0.46) | MAPTPKMLMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106885852-A | A kind of preparation of difunctional integral post for Nitro Polycyclic Aromatic Hydrocarbons and high performance liquid chromatography method for combined use | 北京工业大学 | 2017-06-23 | — | — | CN | claimed |
| CN-106885852-A | A kind of preparation of difunctional integral post for Nitro Polycyclic Aromatic Hydrocarbons and high performance liquid chromatography method for combined use | 北京工业大学 | 2017-06-23 | — | — | CN | disclosed |