Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28224258 | 0.95 | CHRM1 (0.39) | SIGMAR1CHRM1CHRM2GNAO1GNAI3 | |
| SCHEMBL28168619 | 0.87 | NCF1 (0.34) | CHRM1CHRM2GNAO1GNAI3GNAI1 | |
| SCHEMBL28177627 | 0.79 | ACHE (0.34) | SIGMAR1ACHEALDH1A1 | |
| SCHEMBL27713963 | 0.79 | NCF1 (0.52) | GNAO1GNAI3GNAI1ALDH1A1NCF1 | |
| SCHEMBL3865449 | 0.77 | ACHE (0.35) | CHRM1CHRM2GNAO1CHRM3ACHE | |
| SCHEMBL5031515 | 0.76 | CHRM1 (0.47) | SIGMAR1CHRM1CHRM2GNAO1GNAI3 | |
| SCHEMBL27597839 | 0.76 | CACNA1I (0.31) | GNAO1ACHE | |
| SCHEMBL5034030 | 0.75 | CHRM1 (0.49) | SIGMAR1CHRM1CHRM2GNAO1GNAI3 | |
| SCHEMBL3476951 | 0.75 | NCF1 (0.58) | SIGMAR1CHRM1CHRM2GNAO1GNAI3 | |
| SCHEMBL27742769 | 0.75 | SIGMAR1 (0.38) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104684906-B | Nampt inhibitor | 艾伯维公司 | 2017-06-09 | — | — | CN | disclosed |