Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 10/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28155597 | 0.86 | CSNK2A1 (0.58) | RAB9ANPC1TRPV4TUBB4ATUBB | |
| SCHEMBL28845877 | 0.81 | RAB9A (0.56) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL28155536 | 0.81 | RAB9A (0.72) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL14758376 | 0.80 | MEN1 (0.73) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL7905433 | 0.76 | MEN1 (0.54) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL28155497 | 0.75 | RAB9A (0.49) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL28002973 | 0.75 | RAB9A (0.54) | RAB9ANPC1TRPV4TUBB4ATUBB | |
| SCHEMBL28154619 | 0.75 | RAB9A (0.42) | RAB9ANPC1TRPV4MEN1KMT2A | |
| SCHEMBL28154725 | 0.74 | NPC1 (0.47) | RAB9ANPC1TRPV4MEN1KMT2A | |
| SCHEMBL28154618 | 0.74 | NPC1 (0.41) | RAB9ANPC1TRPV4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254534-B | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2017-07-14 | — | — | CN | disclosed |