Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2379547 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL28154591 | 0.76 | RAB9A (0.53) | MEN1KMT2ARAB9ATUBB4ATUBB | |
| SCHEMBL12300962 | 0.75 | MAPT (0.63) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL24590341 | 0.74 | PTGS2 (0.72) | MEN1KMT2ARAB9ATUBB4ATUBB | |
| SCHEMBL16208839 | 0.74 | MEN1 (0.69) | MEN1KMT2ARAB9AARNPC1 | |
| SCHEMBL13513658 | 0.73 | NPC1 (0.70) | MEN1KMT2ARAB9AARNPC1 | |
| SCHEMBL14048211 | 0.73 | MEN1 (0.69) | MEN1KMT2ARAB9AECE1AR | |
| SCHEMBL15134849 | 0.72 | ALDH1A1 (0.52) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL24590484 | 0.72 | VCP (0.65) | MEN1KMT2ARAB9AARNPC1 | |
| SCHEMBL29419331 | 0.72 | VCP (0.65) | MEN1KMT2ARAB9AARNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37094-E1 | Heterocyclic substituted acylaminothiazoles, their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 2001-03-13 | — | — | US | disclosed |
| US-5189049-A | Cholecystokinin and gastrin inhibitors | SANOFI (FR) | 1993-02-23 | — | — | US | disclosed |