Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.56 |
| ▸ | MEN1 | O00255 | 11/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.56 |
| ▸ | NPC1 | O15118 | 11/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14758376 | 0.87 | MEN1 (0.73) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL18029517 | 0.83 | RAB9A (0.79) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL28154591 | 0.81 | RAB9A (0.53) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL28155536 | 0.81 | RAB9A (0.72) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL28002973 | 0.79 | RAB9A (0.54) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL28155597 | 0.79 | CSNK2A1 (0.58) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL28154695 | 0.78 | RAB9A (0.46) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL28845875 | 0.78 | NPC1 (0.52) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL28154610 | 0.78 | NPC1 (0.49) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL28155498 | 0.76 | MEN1 (0.52) | RAB9AMEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254534-B | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2017-07-14 | — | — | CN | disclosed |