Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29935924 | 0.81 | ALDH1A1 (0.37) | ERN1NFE2L2ALDH1A1TSHRKDM4E | |
| SCHEMBL746942 | 0.81 | NFE2L2 (0.41) | ERN1PRKDCNFE2L2ALDH1A1TSHR | |
| SCHEMBL4111524 | 0.81 | ALDH1A1 (0.37) | ERN1NFE2L2ALDH1A1TSHRKDM4E | |
| SCHEMBL746493 | 0.81 | ERN1 (0.44) | ERN1PRKDCALDH1A1TSHRKDM4E | |
| SCHEMBL30963127 | 0.81 | ALDH1A1 (0.37) | ERN1NFE2L2ALDH1A1TSHRKDM4E | |
| SCHEMBL30644382 | 0.79 | PRKDC (0.39) | ERN1PRKDCNFE2L2ALDH1A1TSHR | |
| SCHEMBL29268437 | 0.79 | ERN1 (0.49) | ERN1ALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL29954700 | 0.79 | NFE2L2 (0.39) | ERN1NFE2L2ALDH1A1TSHRKDM4E | |
| SCHEMBL15335119 | 0.79 | ERN1 (0.40) | ERN1PRKDCALDH1A1TSHRKDM4E | |
| SCHEMBL28719128 | 0.79 | ERN1 (0.40) | ERN1PRKDCNFE2L2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106800531-A | A kind of fluorescence probe PMPA and preparation method and application | 山西大学 | 2017-06-06 | — | — | CN | disclosed |