Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24961519 | 0.81 | L3MBTL1 (0.38) | NFE2L2ALDH1A1DYRK1AJAK2MAPK1 | |
| SCHEMBL19629214 | 0.81 | NFE2L2 (0.36) | NFE2L2ALDH1A1DYRK1AJAK2MAPK1 | |
| SCHEMBL29935924 | 0.79 | ALDH1A1 (0.37) | NFE2L2ALDH1A1TSHRFDPSERN1 | |
| SCHEMBL4111524 | 0.79 | ALDH1A1 (0.37) | NFE2L2ALDH1A1TSHRFDPSERN1 | |
| SCHEMBL28154686 | 0.79 | ERN1 (0.41) | NFE2L2ALDH1A1TSHRFDPSERN1 | |
| SCHEMBL30963127 | 0.79 | ALDH1A1 (0.37) | NFE2L2ALDH1A1TSHRFDPSERN1 | |
| SCHEMBL22454610 | 0.79 | NFE2L2 (0.35) | NFE2L2ALDH1A1DYRK1AJAK2MAPK1 | |
| SCHEMBL1662248 | 0.78 | DYRK1A (0.40) | ALDH1A1DYRK1AJAK2MAPK1L3MBTL1 | |
| SCHEMBL30320423 | 0.78 | DYRK1A (0.40) | ALDH1A1DYRK1AJAK2MAPK1L3MBTL1 | |
| SCHEMBL29268437 | 0.78 | ERN1 (0.49) | ALDH1A1ERN1MAPK1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |