Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 11/20 | 0.52 |
| ▸ | MAOB | P27338 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28155510 | 0.89 | GRM4 (0.50) | KDRGRM4ALDH1A1LMNAKDM4E | |
| SCHEMBL367310 | 0.81 | GRM4 (0.72) | KDRGRM4ALDH1A1LMNAKDM4E | |
| SCHEMBL369922 | 0.76 | GRM4 (0.67) | KDRGRM4ALDH1A1LMNAKDM4E | |
| SCHEMBL12639832 | 0.74 | ALDH1A1 (0.59) | ALDH1A1LMNAKDM4EPOLBMAOA | |
| SCHEMBL1745085 | 0.73 | MAOA (0.62) | ALDH1A1LMNAMAOAMAOBMEN1 | |
| SCHEMBL369152 | 0.72 | GRM4 (1.00) | KDRGRM4ALDH1A1LMNAMAOA | |
| SCHEMBL25327043 | 0.71 | MAOA (0.60) | ALDH1A1LMNAMAOAMAOBMEN1 | |
| SCHEMBL1888443 | 0.71 | NPC1 (0.48) | KDRALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL30745793 | 0.70 | GRM4 (0.63) | KDRGRM4ALDH1A1LMNAKDM4E | |
| SCHEMBL5174932 | 0.70 | GRM4 (0.63) | KDRGRM4ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254534-B | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2017-07-14 | — | — | CN | disclosed |