Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | DDX3X | O00571 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4118564 | 0.86 | GAA (0.73) | MEN1KMT2AMAPTDDX3XPOLB | |
| SCHEMBL28217592 | 0.85 | MEN1 (0.66) | MEN1KMT2AMAPTPOLBGAA | |
| SCHEMBL17976484 | 0.82 | CFD (0.60) | MEN1KMT2AMAPTDDX3XPOLB | |
| SCHEMBL17976028 | 0.81 | MAOA (0.59) | MEN1KMT2AMAPTDDX3XBAZ1A | |
| SCHEMBL28156241 | 0.81 | MAPT (0.59) | MEN1KMT2AMAPTDDX3XHTT | |
| SCHEMBL709156 | 0.80 | MEN1 (0.70) | MEN1KMT2AMAPTDDX3XPOLB | |
| SCHEMBL11055960 | 0.79 | MEN1 (0.85) | MEN1KMT2AMAPTDDX3XPOLB | |
| SCHEMBL27880343 | 0.79 | MEN1 (0.70) | MEN1KMT2AMAPTDDX3XPOLB | |
| SCHEMBL6302157 | 0.79 | MEN1 (1.00) | MEN1KMT2AMAPTPOLBCA12 | |
| SCHEMBL1177730 | 0.79 | MEN1 (1.00) | MEN1KMT2AMAPTPOLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106699755-B | A kind of aza-acridine class compound and preparation method thereof and purposes | 清华大学深圳研究生院 | 2018-09-21 | — | — | CN | disclosed |
| CN-106699755-A | Aza-acridine compound and preparation method and application thereof | 清华大学深圳研究生院 | 2017-05-24 | — | — | CN | disclosed |