Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 10/20 | 0.45 |
| ▸ | TUBB | P07437 | 10/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 10/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 10/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 10/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 10/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 10/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 10/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 10/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 10/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 10/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 10/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 10/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 10/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2751742 | 0.75 | TUBB4A (0.49) | FYNPDGFRBTUBB4ATUBBTUBA3C | |
| SCHEMBL28238947 | 0.74 | FYN (0.64) | FYNPDGFRBTUBB4ATUBBTUBA3C | |
| SCHEMBL2751688 | 0.72 | PDE4A (0.53) | FYNPDGFRBTUBB4ATUBBTUBA3C | |
| SCHEMBL20485781 | 0.71 | FYN (1.00) | FYN | |
| Ammonia Solution, Strong SCHEMBL6204421 | 0.69 | FYN (0.52) | FYNKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL28060862 | 0.68 | FYN (0.57) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2753374 | 0.68 | ALDH1A1 (0.48) | FYNERN1KDM4EALDH1A1HPGD | |
| SCHEMBL14003496 | 0.68 | ACHE (0.47) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5686777 | 0.68 | CYP1A1 (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5686772 | 0.68 | CYP1A1 (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103052640-B | Furopyridine Derivatives | 默克专利股份公司 | 2017-06-30 | — | — | CN | claimed |
| CN-103052640-B | Furopyridine Derivatives | 默克专利股份公司 | 2017-06-30 | — | — | CN | disclosed |