Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28157299 | 0.88 | MAPT (0.66) | MAPTMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL28846321 | 0.84 | KMT2A (0.65) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL28157418 | 0.84 | MAPT (0.48) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL28157289 | 0.82 | MAPT (0.61) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL28157420 | 0.81 | MAPT (0.59) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL16337519 | 0.80 | CFTR (0.63) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL28846379 | 0.80 | HPGD (0.52) | MAPTMEN1KMT2ATP53HTT | |
| SCHEMBL28156732 | 0.80 | MAPT (0.44) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL28156717 | 0.80 | MEN1 (0.50) | MAPTMEN1KMT2ATP53HTT | |
| SCHEMBL16088776 | 0.78 | L3MBTL1 (0.62) | MAPTMEN1KMT2ATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105531268-B | Noval chemical compound and its pharmaceutical composition for treating cystic fibrosis | 加拉佩格斯股份有限公司 | 2017-09-12 | — | — | CN | disclosed |